Ethan Hillman’s research focuses on leveraging microbes (bacteria and/or fungi) to solve real-world problems. By engineering microbes or reshaping communities of microbes, we can treat diseases with cost-effective and noninvasive methods, harvest oil with more sustainable approaches, and discover new pharmaceuticals, food additives, and biotechnologies. His research revolves around understanding the biochemical functions of both specific microbes and collections of them and how they affect their surrounding environment.

Hillman’s lab integrates molecular biology techniques, bioinformatic reconstructions of genomes, and principles of microbial ecology to discover the mechanisms behind microbial behavior. Because these principles apply to many microbial communities, our work can be applied in a range of sectors from human health and pharmaceutical to agriculture and energy.

Areas of Expertise

Microbiomes; synthetic biology; genomics; bioinformatics

Education

2021 — Doctor of Philosophy from Purdue University

2015 — Bachelor of Arts from Anderson University

Courses Recently Taught

This is the first laboratory course a student takes and is a prerequisite for all upper-division laboratory courses- required for the major. Students are introduced to the processes of investigative biology and scientific writing. Laboratories cover topics presented in the core lecture courses, BIOL 115 and 116, and introduce a variety of techniques and topics, including field sampling, microscopy, PCR, gel electrophoresis, enzyme biochemistry, physiology, evolution and population biology. The course emphasizes the development of inquiry skills through active involvement in experimental design, data collection and management, statistical analysis, integration of results with information reported in the literature, and writing in a format appropriate for publication. The year culminates in six-week student-designed investigations that reinforce the research skills developed during the year. Evaluation is based on laboratory notebooks, lab performance and scientific papers, as well as oral and written presentations summarizing the independent project. Prerequisite: completion or concurrent enrollment in BIOL 115 or equivalent.

This is the first laboratory course a student takes and is a prerequisite for all upper-division laboratory courses- required for the major. Students are introduced to the processes of investigative biology and scientific writing. Laboratories cover topics presented in the core lecture courses, BIOL 115 and 116, and introduce a variety of techniques and topics, including field sampling, microscopy, PCR, gel electrophoresis, enzyme biochemistry, physiology, evolution and population biology. The course emphasizes the development of inquiry skills through active involvement in experimental design, data collection, statistical analysis, integration of results with information reported in the literature and writing in a format appropriate for publication. The year culminates in six-week student-designed investigations that reinforce the research skills developed during the year. Evaluation is based on short reports, quizzes, lab performance and scientific papers, as well as oral and written presentations based on the independent project. Prerequisite: BIOL 109Y and 115 or equivalent.

This course is required for the major (AP or IB credit can be applied), therefore, biology majors should take this class prior to the junior year. Energy flow is a unifying principle across a range of living systems, from cells to ecosystems. With energy flow as a major theme, this course covers macromolecules, cells, respiration and photosynthesis, physiology and homeostasis, population and community interactions, and ecosystems. Throughout the course, the diversity of life is explored. The course also introduces students to the process of scientific thinking through discussion of research methodology and approaches. No prerequisite. Offered every year.

In this course, students learn the classic techniques of studying bacteria, protists and viruses in medical science and ecology, and practice microbial culture and examine life cycles, cell structure and metabolism and genetics. High-throughput methods of analysis are performed, such as use of the microplate UV-VIS spectrophotometer and whole-genome sequencing. For the final project, each student surveys the microbial community of a particular habitat, using DNA analysis and biochemical methods to identify microbial isolates. This counts toward the upper-level laboratory requirement. Prerequisite: BIOL 109Y-110Y or a chemistry lab course. Prerequisite or corequisite: BIOL 238.